Recombinant Human Centromere protein M (CENPM)

ACP19074

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Specifications

Cat.No	ACP19074	Target Name	CENPM
Target Synonyms	CENPM; C22orf18; ICEN39; PANE1Centromere protein M; CENP-M; Interphase centromere complex protein 39; Proliferation-associated nuclear element protein 1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-180
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9NSP4

Background Information

Uniprot Id

Q9NSP4
Target Species

Human
Target Name

CENPM
Target Full Name

Centromere protein M
Target Function

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
Target Subcellular Location

Nucleus. Cytoplasm. Chromosome, centromere, kinetochore.
Target Tissue Specificity

Isoform 3 is highly expressed in spleen, and intermediately in heart, prostate and ovary. Isoform 3 is highly expressed in resting CD19 B-cells and B-lineage chronic lymphocytic leukemia (B-CLL) cells and weakly expressed in activated B-cells. Isoform 1 i
Target Synonyms

CENPM; C22orf18; ICEN39; PANE1Centromere protein M; CENP-M; Interphase centromere complex protein 39; Proliferation-associated nuclear element protein 1

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Recombinant Human Centromere protein M (CENPM)

Specifications

Immunogen Information

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