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| Cat.No | ACP19393 | Target Name | CENPT |
|---|---|---|---|
| Target Synonyms | C16orf56 ; CENP T ; CENP-T; Cenpt; CENPT_HUMAN; Centromere protein T; Chromosome 16 open reading frame 56; ICEN22 ; Interphase centromere complex protein 22 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-561 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96BT3 |
|---|
Uniprot Id
Q96BT3
Target Species
Human
Target Name
CENPT
Target Full Name
Centromere protein T
Target Function
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis
Target Subcellular Location
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore.
Target Protein Families
CENP-T/CNN1 family
Target Synonyms
C16orf56 ; CENP T ; CENP-T; Cenpt; CENPT_HUMAN; Centromere protein T; Chromosome 16 open reading frame 56; ICEN22 ; Interphase centromere complex protein 22
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