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| Cat.No | ACP16643 | Target Name | CEP85L |
|---|---|---|---|
| Target Synonyms | CEP85L; C6orf204Centrosomal protein of 85 kDa-like; Serologically defined breast cancer antigen NY-BR-15 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5SZL2 |
|---|
Uniprot Id
Q5SZL2
Target Species
Human
Target Name
CEP85L
Target Full Name
Centrosomal protein of 85 kDa-like
Target Function
Plays an essential role in neuronal cell migration.
Target Involvement
A chromosomal aberration involving CEP85L is found in a patient with T-lymphoblastic lymphoma (T-ALL) and an associated myeloproliferative neoplasm (MPN) with eosinophilia. Translocation t(5;6)(q33-34;q23) with PDGFRB. The translocation fuses the 5'-end of CEP85L (isoform 4) to the 3'-end of PDGFRB.
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Target Protein Families
CEP85 family
Target Tissue Specificity
Isoform 1 and isoform 4 are expressed in spleen, lymph, thymus, tonsil and peripheral blood leukocytes, with isoform 1 expressed at higher levels. Isoform 4 is detected in K-562 leukemia cells and in the blood of precursor T lymphoblastic lymphoma (T-ALL)
Target Synonyms
CEP85L; C6orf204Centrosomal protein of 85 kDa-like; Serologically defined breast cancer antigen NY-BR-15
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