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| Cat.No | ACP17417 | Target Name | CDNF |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 25-187 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q49AH0 |
|---|
Uniprot Id
Q49AH0
Target Species
Human
Target Name
CDNF
Target Full Name
Cerebral dopamine neurotrophic factor
Target Function
Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
Target Subcellular Location
Secreted.
Target Protein Families
ARMET family
Target Tissue Specificity
Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum.
Target Synonyms
Arginine rich mutated in early stage tumors like 1; ARMET L1; ARMET like protein 1; ARMET-like protein 1; ARMETL 1; ARMETL1; CDNF; CDNF_HUMAN; Cerebral dopamine neurotrophic factor; Conserved dopamine neurotrophic factor
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