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| Cat.No | ACP12720 | Target Name | CHMP7 |
|---|---|---|---|
| Target Synonyms | CHMP7Charged multivesicular body protein 7; Chromatin-modifying protein 7 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-453 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WUX9 |
|---|
Uniprot Id
Q8WUX9
Target Species
Human
Target Name
CHMP7
Target Full Name
Charged multivesicular body protein 7
Target Function
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway.
Target Subcellular Location
Cytoplasm. Nucleus envelope.
Target Protein Families
SNF7 family
Target Research Area
Signal Transduction
Target Synonyms
CHMP7Charged multivesicular body protein 7; Chromatin-modifying protein 7
Target Background
Involved in several processes, including late endosome to vacuole transport; midbody abscission; and mitotic nuclear division. Located in cytosol; nuclear envelope; and nucleoplasm. Part of ESCRT III complex. Colocalizes with chromatin.
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