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| Cat.No | ACP10439 | Target Name | ALG1 |
|---|---|---|---|
| Target Synonyms | 4-mannosyltransferase; Alg1; ALG1_HUMAN; asparagine-linked glycosylation 1 homolog (yeast; beta-1, 4-mannosyltransferase); asparagine-linked glycosylation 1; beta-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BT22 |
|---|
Uniprot Id
Q9BT22
Target Species
Human
Target Name
ALG1
Target Full Name
Chitobiosyldiphosphodolichol beta-mannosyltransferase
Target Function
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.
Target Involvement
Congenital disorder of glycosylation 1K (CDG1K)
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase group 1 family, Glycosyltransferase 33 subfamily
Target Synonyms
4-mannosyltransferase; Alg1; ALG1_HUMAN; asparagine-linked glycosylation 1 homolog (yeast; beta-1,4-mannosyltransferase); asparagine-linked glycosylation 1; beta-1,4-mannosyltransferase homolog (S. cerevisiae); Asparagine-linked glycosylation protein 1 homolog; Beta 1 4 mannosyltransferase; Beta-1; CDG1K; Chitobiosyldiphosphodolichol beta-mannosyltransferase; GDP Man GlcNAc2 PP dolichol mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; Hmat-1; HMAT1; HMT 1; HMT1; Mannosyltransferase 1; Mannosyltransferase-1; MT 1; MT-1; MT1
Target Background
The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik.
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