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| Cat.No | ACP06686 | Target Name | CLIC3 |
|---|---|---|---|
| Target Synonyms | CLIC3; Chloride intracellular channel protein 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95833 |
|---|
Uniprot Id
O95833
Target Species
Human
Target Name
CLIC3
Target Full Name
Chloride intracellular channel protein 3
Target Function
Can insert into membranes and form chloride ion channels. May participate in cellular growth control.
Target Subcellular Location
Nucleus. Membrane; Single-pass membrane protein. Cytoplasm.
Target Protein Families
Chloride channel CLIC family
Target Tissue Specificity
Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas.
Target Synonyms
CLIC3; Chloride intracellular channel protein 3
Target Background
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.
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