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Recombinant Human Chordin-like protein 2 (CHRDL2)

ACP15862

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15862 Target NameCHRDL2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range26-429Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6WN34
Background Information
  • Uniprot Id

    Q6WN34

  • Target Species

    Human

  • Target Name

    CHRDL2

  • Target Full Name

    Chordin-like protein 2

  • Target Function

    May inhibit BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. Implicated in tumor angiogenesis. May play a role during myoblast and osteoblast differentiation, and maturation.

  • Target Subcellular Location

    [Isoform 1]: Secreted.; [Isoform 2]: Secreted.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.; [Isoform 5]: Cytoplasm.

  • Target Tissue Specificity

    Highly expressed in uterus. Moderately expressed in heart, liver, prostate, testis and ovary. Weakly expressed in skeletal muscle, kidney, spleen, small intestine and colon. Expressed in the secretory epithelial cells of uterine endometrium, fallopian tub

  • Target Synonyms

    BNF-1; BNF1 ; Breast tumor novel factor 1; CHL2 ; chordin like 2; Chordin like protein 2 precursor ; Chordin related protein 2; Chordin-like protein 2; Chordin-related protein 2; Chrdl2; CRDL2_HUMAN; DKFZp586N2124; FKSG37

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