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Recombinant Human F11 protein offers an exceptional resource for researchers focusing on cardiovascular studies, specifically in the area of blood coagulation. Coagulation factor XI, also known as plasma thromboplastin antecedent (PTA), plays a vital role in the intrinsic pathway of the coagulation cascade, converting factor IX to its activated form, factor IXa. This product presents a partial sequence of the human F11 protein (19-387aa), which is expressed in E.coli, ensuring the production of a high-quality recombinant protein. The N-terminal 6xHis tag enables seamless purification and detection in a variety of applications. With a purity greater than 90% as determined by SDS-PAGE, our Recombinant Human F11 protein serves as a trustworthy reagent for your cardiovascular research. The lyophilized powder form allows for easy reconstitution and immediate use in your experiments.
Recombinant Human F11 protein offers an exceptional resource for researchers focusing on cardiovascular studies, specifically in the area of blood coagulation. Coagulation factor XI, also known as plasma thromboplastin antecedent (PTA), plays a vital role in the intrinsic pathway of the coagulation cascade, converting factor IX to its activated form, factor IXa.
This product presents a partial sequence of the human F11 protein (19-387aa), which is expressed in E.coli, ensuring the production of a high-quality recombinant protein. The N-terminal 6xHis tag enables seamless purification and detection in a variety of applications. With a purity greater than 90% as determined by SDS-PAGE, our Recombinant Human F11 protein serves as a trustworthy reagent for your cardiovascular research. The lyophilized powder form allows for easy reconstitution and immediate use in your experiments.
| Cat.No | ACP02302 | Target Name | F11 |
|---|---|---|---|
| Target Synonyms | coagulation factor XI; Coagulation factor XIa light chain; F11; FA11_HUMAN; FXI; MGC141891; Plasma thromboplastin antecedent; Platelet coagulation factor XI ; PTA | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 19-387aa |
| Mol Weight | 45.2kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P03951 |
|---|
Uniprot Id
P03951
Target Species
Human
Target Name
F11
Target Full Name
Coagulation factor XI
Target Function
Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Target Involvement
Factor XI deficiency (FA11D)
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase S1 family, Plasma kallikrein subfamily
Target Tissue Specificity
Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.
Target Research Area
Cardiovascular
Target Synonyms
coagulation factor XI; Coagulation factor XIa light chain; F11; FA11_HUMAN; FXI; MGC141891; Plasma thromboplastin antecedent; Platelet coagulation factor XI ; PTA
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