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| Cat.No | ACP14309 | Target Name | SVBP |
|---|---|---|---|
| Target Synonyms | SVBP; CCDC23; Small vasohibin-binding protein; Coiled coil domain-containing protein 23 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-66 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N300 |
|---|
Uniprot Id
Q8N300
Target Species
Human
Target Name
SVBP
Target Full Name
Small vasohibin-binding protein
Target Function
Enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin. This activity is critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Also required to enhance the solubility and secretion of VASH1 and VASH2. Plays a role in axon and excitatory synapse formation.
Target Subcellular Location
Cytoplasm. Secreted. Cytoplasm, cytoskeleton.
Target Protein Families
SVBP family
Target Synonyms
SVBP; CCDC23; Small vasohibin-binding protein; Coiled coil domain-containing protein 23
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