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Recombinant Human Coiled-coil domain-containing protein 6 (CCDC6)

ACP17806

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17806 Target NameCCDC6
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range2-474Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ16204
Background Information
  • Uniprot Id

    Q16204

  • Target Species

    Human

  • Target Name

    CCDC6

  • Target Full Name

    Coiled-coil domain-containing protein 6

  • Target Involvement

    A chromosomal aberration involving CCDC6 is found in papillary thyroid carcinomas (PTCs). Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton. Note=May be a cytoskeletal protein.

  • Target Tissue Specificity

    Ubiquitously expressed.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    CCDC 6; CCDC6; CCDC6_HUMAN; Coiled coil domain containing 6; Coiled coil domain containing protein 6; Coiled-coil domain-containing protein 6; D10S170; FLJ32286; H4; Papillary thyroid carcinoma encoded protein; Papillary thyroid carcinoma-encoded protein; Protein H4; PTC; TPC; TST 1; TST1

  • Target Background

    This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.

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