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Recombinant Human Collagen alpha-2 (IX) chain (COL9A2)

ACP18264

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18264 Target NameCOL9A2
Target SynonymsCO9A2_HUMAN; COL9A2; Collagen alpha-2(IX) chainFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range24-689
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ14055
Background Information
  • Uniprot Id

    Q14055

  • Target Species

    Human

  • Target Name

    COL9A2

  • Target Full Name

    Collagen alpha-2(IX) chain

  • Target Function

    Structural component of hyaline cartilage and vitreous of the eye.

  • Target Involvement

    Multiple epiphyseal dysplasia 2 (EDM2); Intervertebral disc disease (IDD); Stickler syndrome 5 (STL5)

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix.

  • Target Protein Families

    Fibril-associated collagens with interrupted helices (FACIT) family

  • Target Synonyms

    CO9A2_HUMAN; COL9A2; Collagen alpha-2(IX) chain

  • Target Background

    This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. This chain is unusual in that, unlike the other two type IX alpha chains, it contains a covalently attached glycosaminoglycan side chain. Mutations in this gene are associated with multiple epiphyseal dysplasia.

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