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Recombinant Human Collagen alpha-2 (VIII) chain (COL8A2)

ACP23488

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Specifications

Cat.No	ACP23488	Target Name	COL8A2
Target Synonyms	COL8A2Collagen alpha-2(VIII) chain; Endothelial collagen	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	29-703
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P25067

Background Information

Uniprot Id

P25067
Target Species

Human
Target Name

COL8A2
Target Full Name

Collagen alpha-2(VIII) chain
Target Function

Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.
Target Involvement

Corneal dystrophy, Fuchs endothelial, 1 (FECD1); Corneal dystrophy, posterior polymorphous, 2 (PPCD2)
Target Subcellular Location

Secreted, extracellular space, extracellular matrix, basement membrane.
Target Tissue Specificity

Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve b
Target Synonyms

COL8A2Collagen alpha-2(VIII) chain; Endothelial collagen

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Recombinant Human Collagen alpha-2 (VIII) chain (COL8A2)

Specifications

Immunogen Information

Inquire Recombinant Human Collagen alpha-2 (VIII) chain (COL8A2) Now

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