Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
Explore the intricacies of the immune response and complement system with our Recombinant Human C1QA protein. Complement C1q subcomponent subunit A (C1QA) is a crucial element of the classical complement pathway, participating in the activation process and contributing to the overall innate immune response. This product contains the full length of the mature C1QA protein (23-245aa), ensuring a high-quality and accurate representation for your research needs. Expressed in E.coli, the protein is equipped with an N-terminal 10xHis-tag and a C-terminal Myc-tag, facilitating efficient purification and detection procedures. With a purity greater than 85% as determined by SDS-PAGE, our Recombinant Human C1QA protein is available in both liquid and lyophilized powder forms, offering flexibility and reliability for immunology researchers and complement system investigations.
Explore the intricacies of the immune response and complement system with our Recombinant Human C1QA protein. Complement C1q subcomponent subunit A (C1QA) is a crucial element of the classical complement pathway, participating in the activation process and contributing to the overall innate immune response.
This product contains the full length of the mature C1QA protein (23-245aa), ensuring a high-quality and accurate representation for your research needs. Expressed in E.coli, the protein is equipped with an N-terminal 10xHis-tag and a C-terminal Myc-tag, facilitating efficient purification and detection procedures. With a purity greater than 85% as determined by SDS-PAGE, our Recombinant Human C1QA protein is available in both liquid and lyophilized powder forms, offering flexibility and reliability for immunology researchers and complement system investigations.
| Cat.No | ACP02240 | Target Name | C1QA |
|---|---|---|---|
| Target Synonyms | C1qa; C1QA_HUMAN; Complement C1q subcomponent subunit A; Complement component 1 q subcomponent A chain; Complement component 1 q subcomponent alpha polypeptide; Complement component C1q A chain | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 23-245aa |
| Mol Weight | 30.7 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P02745 |
|---|
Uniprot Id
P02745
Target Species
Human
Target Name
C1QA
Target Full Name
Complement C1q subcomponent subunit A
Target Function
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Target Involvement
Complement component C1q deficiency (C1QD)
Target Subcellular Location
Secreted.
Target Research Area
Immunology
Target Synonyms
C1qa; C1QA_HUMAN; Complement C1q subcomponent subunit A; Complement component 1 q subcomponent A chain; Complement component 1 q subcomponent alpha polypeptide; Complement component C1q A chain
Target Background
This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
