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| Cat.No | ACP24281 | Target Name | C6 |
|---|---|---|---|
| Target Synonyms | AW111623; C6; CO6_HUMAN; Complement component 6; Complement component C6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P13671 |
|---|
Uniprot Id
P13671
Target Species
Human
Target Name
C6
Target Full Name
Complement component C6
Target Function
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Target Involvement
Complement component 6 deficiency (C6D)
Target Subcellular Location
Secreted.
Target Protein Families
Complement C6/C7/C8/C9 family
Target Synonyms
AW111623; C6; CO6_HUMAN; Complement component 6; Complement component C6
Target Background
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.
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