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Recombinant Human COP9 signalosome complex subunit 7b (COPS7B)

ACP11509

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Specifications

Cat.No	ACP11509	Target Name	COPS7B
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	2-264	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9H9Q2

Background Information

Uniprot Id

Q9H9Q2
Target Species

Human
Target Name

COPS7B
Target Full Name

COP9 signalosome complex subunit 7b
Target Function

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Target Subcellular Location

Cytoplasm. Nucleus.
Target Protein Families

CSN7/EIF3M family, CSN7 subfamily
Target Synonyms

COP9 Complex Homolog Subunit 7b; COP9 Constitutive Photomorphogenic Homolog Subunit 7b; COP9 Signalasome Subunit 7b; COP9 signalosome complex subunit 7b; COPS7B; CSN7B_HUMAN; JAB1 Containing Signalosome Subunit 7b; JAB1-containing signalosome subunit 7b; SGN7b; Signalosome subunit 7b

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Recombinant Human COP9 signalosome complex subunit 7b (COPS7B)

Specifications

Immunogen Information

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