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| Cat.No | ACP03876 | Target Name | SERPINA6 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | Yeast |
| Expression Range | 23-405aa | Mol Weight | 44.6kDa |
| Protein Length | Full Length of Mature Protein | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P08185 |
|---|
Uniprot Id
P08185
Target Species
Human
Target Name
SERPINA6
Target Full Name
Corticosteroid-binding globulin
Target Function
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Target Involvement
Corticosteroid-binding globulin deficiency (CBG deficiency)
Target Subcellular Location
Secreted.
Target Protein Families
Serpin family
Target Tissue Specificity
Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.
Target Research Area
Transport
Target Synonyms
CBG; CBG_HUMAN; corticosteroid binding globulin; Corticosteroid-binding globulin; serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6; Serpin A6; serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6; Serpina6; Transcortin
Target Background
This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.
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