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| Cat.No | ACP00848 | Target Name | CKM |
|---|---|---|---|
| Target Synonyms | (Creatine kinase M chain)(Creatine phosphokinase M-type)(CPK-M)(M-CK) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-381aa |
| Mol Weight | 70.6 kDa | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P06732 |
|---|
Uniprot Id
P06732
Target Species
Human
Target Name
CKM
Target Full Name
Creatine kinase M-type
Target Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Target Subcellular Location
Cytoplasm.
Target Protein Families
ATP:guanido phosphotransferase family
Target Research Area
Cancer
Target Synonyms
(Creatine kinase M chain)(Creatine phosphokinase M-type)(CPK-M)(M-CK)
Target Background
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
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