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| Cat.No | ACP09406 | Target Name | CDK11A |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 5-216aa | Mol Weight | 54.1kD |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UQ88 |
|---|
Uniprot Id
Q9UQ88
Target Species
Human
Target Name
CDK11A
Target Full Name
Cyclin-dependent kinase 11A
Target Function
Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Target Tissue Specificity
Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.
Target Research Area
Apoptosis
Target Synonyms
CD11A_HUMAN; CDC2L2; CDC2L3; CDK11; CDK11 p110; CDK11 p46; CDK11 p58; CDK11A; Cell division cycle 2 like 2 (PITSLRE proteins); Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Cyclin-dependent kinase 11A; Galactosyltransferase-associated protein kinase p58/GTA; p58GTA; PITSLRE; PITSLRE B; PITSLRE protein kinase beta; PITSLRE serine/threonine-protein kinase CDC2L2; PITSLREB
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