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| Cat.No | ACP23577 | Target Name | CCNO |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-350 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P22674 |
|---|
Uniprot Id
P22674
Target Species
Human
Target Name
CCNO
Target Full Name
Cyclin-O
Target Function
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking.
Target Involvement
Ciliary dyskinesia, primary, 29 (CILD29)
Target Subcellular Location
Cytoplasm. Nucleus, nucleolus.
Target Protein Families
Cyclin family
Target Tissue Specificity
Present in respiratory cells (at protein level).
Target Synonyms
CCNO; CCNO_HUMAN; CCNU; Cyclin domain containing; Cyclin like uracil DNA glycosylase; Cyclin O; Cyclin U; Cyclin-O; DGU; EC 3.2.2.; UDG2; UNG2; Uracil DNA glycolylase 2; Uracil DNA glycosylase cyclin like
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