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Recombinant Human Cysteine-rich with EGF-like domain protein 1 (CRELD1), Truncated

ACP07848

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP07848 Target NameCRELD1
Target SynonymsCRELD1; CIRRIN; UNQ188/PRO214; Protein disulfide isomerase CRELD1; Cysteine-rich with EGF-like domain protein 1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ96HD1
Background Information
  • Uniprot Id

    Q96HD1

  • Target Species

    Human

  • Target Name

    CRELD1

  • Target Full Name

    Protein disulfide isomerase CRELD1

  • Target Function

    Protein disulfide isomerase. Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane.

  • Target Involvement

    Atrioventricular septal defect 2 (AVSD2)

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    CRELD family

  • Target Tissue Specificity

    Highly expressed in fetal lung, liver, kidney, adult heart, brain and skeletal muscle. Weakly expressed in placenta, fetal brain, and adult lung, liver, kidney and pancreas.

  • Target Synonyms

    CRELD1; CIRRIN; UNQ188/PRO214; Protein disulfide isomerase CRELD1; Cysteine-rich with EGF-like domain protein 1

  • Target Background

    This gene encodes a member of a subfamily of epidermal growth factor-related proteins. The encoded protein is characterized by a cysteine-rich with epidermal growth factor-like domain. This protein may function as a cell adhesion molecule. Mutations in this gene are the cause of atrioventricular septal defect. Alternate splicing results in multiple transcript variants.

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