Recombinant Human Cytochrome P450 2W1 (CYP2W1)

Cat.No	ACP14523	Target Name	CYP2W1
Target Synonyms	CP2W1_HUMAN; CYP2W 1; CYP2W1; CYPIIW1; Cytochrome P450 2W1; Cytochrome P450; family 2; subfamily W; polypeptide 1; MGC34287	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-490
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP14523

Target Name

CYP2W1

Target Synonyms

CP2W1_HUMAN; CYP2W 1; CYP2W1; CYPIIW1; Cytochrome P450 2W1; Cytochrome P450; family 2; subfamily W; polypeptide 1; MGC34287

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-490

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q8TAV3

Background Information

Uniprot Id

Q8TAV3
Target Species

Human
Target Name

CYP2W1
Target Full Name

Cytochrome P450 2W1
Target Function

A cytochrome P450 monooxygenase that may play a role in retinoid and phospholipid metabolism. Catalyzes the hydroxylation of saturated carbon hydrogen bonds. Hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may regulate atRA clearance. Other retinoids such as all-trans retinol and all-trans retinal are potential endogenous substrates. Catalyzes both epoxidation of double bonds and hydroxylation of carbon hydrogen bonds of the fatty acyl chain of 1-acylphospholipids/2-lysophospholipids. Can metabolize various lysophospholipids classes including lysophosphatidylcholines (LPCs), lysophosphatidylinositols (LPIs), lysophosphatidylserines (LPSs), lysophosphatidylglycerols (LPGs), lysophosphatidylethanolamines (LPEs) and lysophosphatidic acids (LPAs). Has low or no activity toward 2-acylphospholipids/1-lysophospholipids, diacylphospholipids and free fatty acids. May play a role in tumorigenesis by activating procarcinogens such as aflatoxin B1, polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
Target Subcellular Location

Endoplasmic reticulum lumen. Cell membrane. Microsome membrane.
Target Protein Families

Cytochrome P450 family
Target Tissue Specificity

Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors.
Target Synonyms

CP2W1_HUMAN; CYP2W 1; CYP2W1; CYPIIW1; Cytochrome P450 2W1; Cytochrome P450; family 2; subfamily W; polypeptide 1; MGC34287
Target Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.

Recombinant Human Cytochrome P450 2W1 (CYP2W1)

Specifications

Immunogen Information

Inquire Recombinant Human Cytochrome P450 2W1 (CYP2W1) Now

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