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| Cat.No | ACP09092 | Target Name | CYP4Z1 |
|---|---|---|---|
| Target Synonyms | CYP4Z1; UNQ3060/PRO9882Cytochrome P450 4Z1; EC 1.14.14.1; CYPIVZ1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86W10 |
|---|
Uniprot Id
Q86W10
Target Species
Human
Target Name
CYP4Z1
Target Full Name
Cytochrome P450 4Z1
Target Function
A cytochrome P450 monooxygenase that catalyzes the in-chain oxidation of fatty acids. Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates lauric and myristic acids predominantly at the omega-4 and omega-2 positions, respectively. Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Displays an absolute stereoselectivity in the epoxidation of arachidonic acid producing the 14(S),15(R)-epoxyeicosatrienoic acid (EET) enantiomer. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein.
Target Protein Families
Cytochrome P450 family
Target Tissue Specificity
Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal expression is found in all other tested tissues.
Target Synonyms
CYP4Z1; UNQ3060/PRO9882Cytochrome P450 4Z1; EC 1.14.14.1; CYPIVZ1
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