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| Cat.No | ACP09532 | Target Name | DYNC1LI1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-523 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y6G9 |
|---|
Uniprot Id
Q9Y6G9
Target Species
Human
Target Name
DYNC1LI1
Target Full Name
Cytoplasmic dynein 1 light intermediate chain 1
Target Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Target Subcellular Location
Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families
Dynein light intermediate chain family
Target Synonyms
Cytoplasmic dynein 1 light intermediate chain 1; cytosolic; DC1L1_HUMAN; DLC-A; DNCLI1; dync1li1; Dynein cytoplasmic 1 light intermediate chain 1; Dynein cytoplasmic light intermediate polypeptide 1; Dynein light chain A; Dynein light intermediate chain 1; Dynein light intermediate chain 1 cytosolic; FLJ10219; LIC1
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