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| Cat.No | ACP15545 | Target Name | PLA2G4D |
|---|---|---|---|
| Target Synonyms | cPLA2 delta; cPLA2-delta; cPLA2delta; Cytosolic phospholipase A2 delta; PA24D_HUMAN; Phospholipase A2 group IVD; phospholipase A2; group IVD (cytosolic); Pla2g4d | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86XP0 |
|---|
Uniprot Id
Q86XP0
Target Species
Human
Target Name
PLA2G4D
Target Full Name
Cytosolic phospholipase A2 delta
Target Function
Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has a preference for linoleic acid at the sn-2 position.
Target Subcellular Location
Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side.
Target Tissue Specificity
Expressed in stratified squamous epithelia, such as those in skin and cervix, but not in other tissues. Strongly expressed in the upper spinous layer of the psoriatic epidermis, expressed weakly and discontinuously in atopic dermatitis and mycosis fungoid
Target Synonyms
cPLA2 delta; cPLA2-delta; cPLA2delta; Cytosolic phospholipase A2 delta; PA24D_HUMAN; Phospholipase A2 group IVD; phospholipase A2; group IVD (cytosolic); Pla2g4d
Target Background
The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 [PubMed 14709560]).
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