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| Cat.No | ACP16919 | Target Name | PLA2G4F |
|---|---|---|---|
| Target Synonyms | cPLA2-zeta; Cytosolic phospholipase A2 zeta; DKFZp666G192; DKFZp781B229; PA24F_HUMAN; Phospholipase A2 group IVF; Pla2g4f; PLA2G4FZ | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q68DD2 |
|---|
Uniprot Id
Q68DD2
Target Species
Human
Target Name
PLA2G4F
Target Full Name
Cytosolic phospholipase A2 zeta
Target Function
Has calcium-dependent phospholipase and lysophospholipase activities with a potential role in membrane lipid remodeling and biosynthesis of lipid mediators. Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity). Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis. In myocardial mitochondria, plays a major role in arachidonate release that is metabolically channeled to the formation of cardioprotective eicosanoids, epoxyeicosatrienoates (EETs).
Target Subcellular Location
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Mitochondrion.
Target Tissue Specificity
Expressed in myocardium (at protein level).
Target Synonyms
cPLA2-zeta; Cytosolic phospholipase A2 zeta; DKFZp666G192; DKFZp781B229; PA24F_HUMAN; Phospholipase A2 group IVF; Pla2g4f; PLA2G4FZ
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