Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The pipeline for the recombinant Human DRD2 protein production in e.coli cells consists of the following consecutive steps: construction of the expression vector encoding the Human DRD2 protein (214-373aa), its transformation into e.coli cells, high-density cultivation and induction of the positive cells, cell lysis, and expression analysis. The protein features a N-terminal 10xHis tag and C-terminal Myc tag fusion. The resulting recombinant Human DRD2 protein is purified from the cell lysate through affinity purification, and its purity is greater than 85% determined by the SDS-PAGE.
The pipeline for the recombinant Human DRD2 protein production in e.coli cells consists of the following consecutive steps: construction of the expression vector encoding the Human DRD2 protein (214-373aa), its transformation into e.coli cells, high-density cultivation and induction of the positive cells, cell lysis, and expression analysis. The protein features a N-terminal 10xHis tag and C-terminal Myc tag fusion. The resulting recombinant Human DRD2 protein is purified from the cell lysate through affinity purification, and its purity is greater than 85% determined by the SDS-PAGE.
| Cat.No | ACP01813 | Target Name | DRD2 |
|---|---|---|---|
| Target Synonyms | DRD2; D(2 dopamine receptor; Dopamine D2 receptor | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 214-373aa |
| Mol Weight | 25.8 kDa | Protein Length | Partial |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P14416 |
|---|
Uniprot Id
P14416
Target Species
Human
Target Name
DRD2
Target Full Name
D(2) dopamine receptor
Target Function
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
[Isoform 1]: Expressed in the anterior pituitary gland.; [Isoform 2]: Expressed in the anterior pituitary gland.
Target Research Area
G-protein coupled receptor, Receptor, Transducer
Target Synonyms
DRD2; D(2 dopamine receptor; Dopamine D2 receptor
Target Background
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
