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Recombinant Human DCN1-like protein 3 (DCUN1D3)

ACP14950

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Specifications

Cat.No	ACP14950	Target Name	DCUN1D3
Target Synonyms	DCUN1D3; SCCRO3DCN1-like protein 3; DCUN1 domain-containing protein 3; Defective in cullin neddylation protein 1-like protein 3; Squamous cell carcinoma-related oncogene 3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-304
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IWE4

Background Information

Uniprot Id

Q8IWE4
Target Species

Human
Target Name

DCUN1D3
Target Full Name

DCN1-like protein 3
Target Function

Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and may play a role in the cell cycle progression by regulating the SCF ubiquitin E3 ligase complex, after UV damage. At the cell membrane, can promote and as well inhibit cullins neddylation.
Target Subcellular Location

Cell membrane. Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
Target Tissue Specificity

Tends to be down-regulated in different type of cancers, including lung neuroendocrine carcinoma, thyroid Huerthle cell carcinoma and lung squamous cell carcinoma. Mostly expressed in testis and brain. Highly expressed in liver, bladder and renal normal t
Target Synonyms

DCUN1D3; SCCRO3DCN1-like protein 3; DCUN1 domain-containing protein 3; Defective in cullin neddylation protein 1-like protein 3; Squamous cell carcinoma-related oncogene 3

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Recombinant Human DCN1-like protein 3 (DCUN1D3)

Specifications

Immunogen Information

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