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| Cat.No | ACP12354 | Target Name | DCUN1D5 |
|---|---|---|---|
| Target Synonyms | DCUN1D5DCN1-like protein 5; DCUN1 domain-containing protein 5; Defective in cullin neddylation protein 1-like protein 5 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-237 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BTE7 |
|---|
Uniprot Id
Q9BTE7
Target Species
Human
Target Name
DCUN1D5
Target Full Name
DCN1-like protein 5
Target Function
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth.
Target Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, spindle.
Target Tissue Specificity
Weakly expressed in testis, skin and immune tissues (thymus, spleen and lymph nodes).
Target Synonyms
DCUN1D5DCN1-like protein 5; DCUN1 domain-containing protein 5; Defective in cullin neddylation protein 1-like protein 5
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