Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP03425 | Target Name | DEDD |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-318aa | Mol Weight | 63.8kDa |
| Protein Length | Full length | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75618 |
|---|
Uniprot Id
O75618
Target Species
Human
Target Name
DEDD
Target Full Name
Death effector domain-containing protein
Target Function
A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro.
Target Subcellular Location
Cytoplasm. Nucleus, nucleolus.
Target Tissue Specificity
Widely expressed with highest levels in testis.
Target Research Area
Cell Biology
Target Synonyms
CASP8IP1; Death effector domain containing; Death effector domain containing protein; Death effector domain containing testicular molecule; Death effector domain-containing protein; Death effector domain-containing testicular molecule; DEDD 1; dedD; DEDD_HUMAN; DEDD1; DEDPro 1; DEDPro1; DEFT; FLDED 1; FLDED-1; FLDED1; KE 05; KE05; OTTHUMP00000031822
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
