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| Cat.No | ACP16770 | Target Name | PDSS1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-415 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5T2R2 |
|---|
Uniprot Id
Q5T2R2
Target Species
Human
Target Name
PDSS1
Target Full Name
All trans-polyprenyl-diphosphate synthase PDSS1
Target Function
Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone. Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9)and ubiquinone-10 (Q10) respectively. The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry.
Target Involvement
Coenzyme Q10 deficiency, primary, 2 (COQ10D2)
Target Subcellular Location
Mitochondrion.
Target Protein Families
FPP/GGPP synthase family
Target Synonyms
PDSS1; DPS1; TPRTDecaprenyl-diphosphate synthase subunit 1; EC 2.5.1.91; All-trans-decaprenyl-diphosphate synthase subunit 1; Decaprenyl pyrophosphate synthase subunit 1; Trans-prenyltransferase 1; TPT 1
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