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| Cat.No | ACP00728 | Target Name | DNER |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 35-640aa | Mol Weight | 71.59999999999999 |
| Protein Length | Partial | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NFT8 |
|---|
Uniprot Id
Q8NFT8
Target Species
Human
Target Name
DNER
Target Full Name
Delta and Notch-like epidermal growth factor-related receptor
Target Function
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Expressed in brain, spinal cord and adrenal gland.
Target Research Area
Neuroscience
Target Synonyms
bet; Brain EGF repeat-containing transmembrane protein; Bret; Delta and Notch-like epidermal growth factor-related receptor; Delta notch like EGF repeat containing transmembrane; Delta/notch like EGF repeat containing; Delta/notch-like EGF-related receptor; Dner; DNER_HUMAN; PRO299; Transmembrane protein Bet; UNQ26
Target Background
Predicted to enable Notch binding activity. Involved in central nervous system development. Located in dendrite; early endosome; and plasma membrane.
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