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| Cat.No | ACP16025 | Target Name | DENND5A |
|---|---|---|---|
| Target Synonyms | DENND5A; KIAA1091; RAB6IP1DENN domain-containing protein 5A; Rab6-interacting protein 1; Rab6IP1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6IQ26 |
|---|
Uniprot Id
Q6IQ26
Target Species
Human
Target Name
DENND5A
Target Full Name
DENN domain-containing protein 5A
Target Function
Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth.
Target Involvement
Epileptic encephalopathy, early infantile, 49 (EIEE49)
Target Subcellular Location
Golgi apparatus membrane.
Target Protein Families
RAB6IP1 family
Target Synonyms
DENND5A; KIAA1091; RAB6IP1DENN domain-containing protein 5A; Rab6-interacting protein 1; Rab6IP1
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