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| Cat.No | ACP15483 | Target Name | DHFR2 |
|---|---|---|---|
| Target Synonyms | DHFR2; DHFRL1; DHFRP4Dihydrofolate reductase 2; mitochondrial; Dihydrofolate reductase; mitochondrial; EC 1.5.1.3; Dihydrofolate reductase-like protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-187 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86XF0 |
|---|
Uniprot Id
Q86XF0
Target Species
Human
Target Name
DHFR2
Target Full Name
Dihydrofolate reductase 2, mitochondrial
Target Function
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.
Target Subcellular Location
Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Target Protein Families
Dihydrofolate reductase family
Target Tissue Specificity
Expressed in numerous cell lines.
Target Synonyms
DHFR2; DHFRL1; DHFRP4Dihydrofolate reductase 2; mitochondrial; Dihydrofolate reductase; mitochondrial; EC 1.5.1.3; Dihydrofolate reductase-like protein 1
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