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| Cat.No | ACP17922 | Target Name | DIXDC1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-683 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q155Q3 |
|---|
Uniprot Id
Q155Q3
Target Species
Human
Target Name
DIXDC1
Target Full Name
Dixin
Target Function
Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.
Target Subcellular Location
Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm.; [Isoform 2]: Cytoplasm.
Target Protein Families
DIXDC1 family
Target Tissue Specificity
Ubiquitously expressed with higher expression in cardiac and skeletal muscles.
Target Synonyms
CCD1; Ccd1Aalpha1L; Ccd1Abeta1L; Ccd1BalphaL; Ccd1BbetaL; Ccd1CL; Coiled coil DIX1 ; Coiled coil protein DIX1 ; Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain containing 1; DIX domain containing protein 1; DIX domain-containing protein 1; DIXC1_HUMAN; DIXDC1; Dixin; KIAA1735
Target Background
The protein encoded by this gene is a positive regulator of the Wnt signaling pathway. The encoded protein is found associated with gamma tubulin at the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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