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| Cat.No | ACP22957 | Target Name | POLR2H |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-150 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P52434 |
|---|
Uniprot Id
P52434
Target Species
Human
Target Name
POLR2H
Target Full Name
DNA-directed RNA polymerases I, II, and III subunit RPABC3
Target Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
Eukaryotic RPB8 RNA polymerase subunit family
Target Synonyms
POLR2H; DNA-directed RNA polymerases I; II; and III subunit RPABC3; RNA polymerases I; II; and III subunit ABC3; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I; II; and III 17.1 kDa polypeptide; RPB17; RPB8 homolog; hRPB8
Target Background
The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Alternative splicing results in multiple transcript variants of this gene.
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