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| Cat.No | ACP09671 | Target Name | RAD54B |
|---|---|---|---|
| Target Synonyms | RAD54B; DNA repair and recombination protein RAD54B; EC 3.6.4.-; RAD54 homolog B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y620 |
|---|
Uniprot Id
Q9Y620
Target Species
Human
Target Name
RAD54B
Target Full Name
DNA repair and recombination protein RAD54B
Target Function
Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.
Target Subcellular Location
Nucleus.
Target Protein Families
SNF2/RAD54 helicase family
Target Tissue Specificity
Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.
Target Synonyms
RAD54B; DNA repair and recombination protein RAD54B; EC 3.6.4.-; RAD54 homolog B
Target Background
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
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