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| Cat.No | ACP20305 | Target Name | OST4 |
|---|---|---|---|
| Target Synonyms | OST4; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P0C6T2 |
|---|
Uniprot Id
P0C6T2
Target Species
Human
Target Name
OST4
Target Full Name
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4
Target Function
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Specifically involved in maintaining stability of STT3A-containing OST complexes
Target Subcellular Location
Endoplasmic reticulum. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Note=The single transmembrane helix has a kink in the middle of the transmembrane span.
Target Protein Families
OST4 family
Target Synonyms
OST4; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4
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