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Recombinant Human Dual specificity protein phosphatase 7 (DUSP7)

ACP18424

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Specifications

Cat.No	ACP18424	Target Name	DUSP7
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-419	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q16829

Background Information

Uniprot Id

Q16829
Target Species

Human
Target Name

DUSP7
Target Full Name

Dual specificity protein phosphatase 7
Target Function

Dual specificity protein phosphatase. Shows high activity towards MAPK1/ERK2. Also has lower activity towards MAPK14 and MAPK8. In arrested oocytes, plays a role in meiotic resumption. Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in oocytes, probably by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB. May also inactivate PRKCA and/or PRKCG. Also important in oocytes for normal chromosome alignment on the metaphase plate and progression to anaphase, where it might regulate activity of the spindle-assembly checkpoint (SAC) complex.
Target Subcellular Location

Cytoplasm.
Target Protein Families

Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
Target Tissue Specificity

Strongly expressed in liver. Expressed at significantly higher levels in malignant hematopoietic cells than in corresponding non-malignant cells.
Target Synonyms

Dual specificity phosphatase 7; Dual specificity protein phosphatase 7; Dual specificity protein phosphatase PYST2; DUS7_HUMAN; Dusp7; Jnk Stimulatory Phosphatase 1; JSP1; MAP kinase phosphatase X; MKPX; PYST2

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Recombinant Human Dual specificity protein phosphatase 7 (DUSP7)

Specifications

Immunogen Information

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