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| Cat.No | ACP19549 | Target Name | DYM |
|---|---|---|---|
| Target Synonyms | DYMDymeclin; Dyggve-Melchior-Clausen syndrome protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-669 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7RTS9 |
|---|
Uniprot Id
Q7RTS9
Target Species
Human
Target Name
DYM
Target Full Name
Dymeclin
Target Function
Necessary for correct organization of Golgi apparatus. Involved in bone development.
Target Involvement
Dyggve-Melchior-Clausen syndrome (DMC); Smith-McCort dysplasia 1 (SMC1)
Target Subcellular Location
Cytoplasm. Golgi apparatus. Membrane; Lipid-anchor. Note=Sequence analysis programs clearly predict 1 transmembrane region. However, PubMed:18996921 shows that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol.
Target Protein Families
Dymeclin family
Target Tissue Specificity
Expressed in most embryo-fetal and adult tissues. Abundant in primary chondrocytes, osteoblasts, cerebellum, kidney, lung, stomach, heart, pancreas and fetal brain. Very low or no expression in the spleen, thymus, esophagus, bladder and thyroid gland.
Target Synonyms
DYMDymeclin; Dyggve-Melchior-Clausen syndrome protein
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