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| Cat.No | ACP12698 | Target Name | DNAAF4 |
|---|---|---|---|
| Target Synonyms | Dyslexia susceptibility 1 candidate 1; Dyslexia susceptibility 1 candidate gene 1 protein; DYX1; DYX1C1; DYXC1; DYXC1_HUMAN; EKN1; FLJ37882; MGC70618; RD | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-420 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WXU2 |
|---|
Uniprot Id
Q8WXU2
Target Species
Human
Target Name
DNAAF4
Target Full Name
Dynein axonemal assembly factor 4
Target Function
Axonemal dynein assembly factor required for ciliary motility. Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity.
Target Involvement
Dyslexia 1 (DYX1); Ciliary dyskinesia, primary, 25 (CILD25)
Target Subcellular Location
Nucleus. Cytoplasm. Dynein axonemal particle. Cell projection, neuron projection.
Target Tissue Specificity
Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells.
Target Synonyms
Dyslexia susceptibility 1 candidate 1; Dyslexia susceptibility 1 candidate gene 1 protein; DYX1; DYX1C1; DYXC1; DYXC1_HUMAN; EKN1; FLJ37882; MGC70618; RD
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