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Recombinant Human E3 ubiquitin-protein ligase NEURL1B (NEURL1B)

ACP21821

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21821 Target NameNEURL1B
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-555Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDA8MQ27
Background Information
  • Uniprot Id

    A8MQ27

  • Target Species

    Human

  • Target Name

    NEURL1B

  • Target Full Name

    E3 ubiquitin-protein ligase NEURL1B

  • Target Function

    E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands.

  • Target Subcellular Location

    Cytoplasm.

  • Target Tissue Specificity

    Highest expression in brain, prostate and small intestine. In the brain the levels are higher in fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar cortex, optic nerve and the frontal lobe.

  • Target Synonyms

    E3 ubiquitin-protein ligase NEURL1B; E3 ubiquitin-protein ligase NEURL3; hNeur2; NEU1B_HUMAN; Neur2; neuralized-2 alternative protein; neuralized-2; Neuralized-like protein 1B; Neuralized-like protein 3; NEURL1B; NEURL3

  • Target Background

    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent endocytosis. Located in actin cytoskeleton and cytosol.

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