Recombinant Human Ecto-NOX disulfide-thiol exchanger 2 (ENOX2)

Cat.No	ACP18664	Target Name	ENOX2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-610	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP18664

Target Name

ENOX2

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-610

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q16206

Background Information

Uniprot Id

Q16206
Target Species

Human
Target Name

ENOX2
Target Full Name

Ecto-NOX disulfide-thiol exchanger 2
Target Function

May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock.
Target Subcellular Location

Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.
Target Protein Families

ENOX family
Target Tissue Specificity

Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Not found in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed in
Target Research Area

Cancer
Target Synonyms

APK1; APK1 antigen; COVA1; Cytosolic ovarian carcinoma antigen 1; Ecto NOX disulfide thiol exchanger 2; ENOX 2; ENOX2; ENOX2_HUMAN; OTTHUMP00000024021; OTTHUMP00000024022; Protein disulfide-thiol oxidoreductase; tNOX; Tumor associated hydroquinone oxidase; Tumor-associated hydroquinone oxidase
Target Background

This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants.

Recombinant Human Ecto-NOX disulfide-thiol exchanger 2 (ENOX2)

Specifications

Immunogen Information

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