Recombinant Human Elongation factor 1-delta (EEF1D)

The expression region of this recombinant Human EF1D covers amino acids 2-281. The calculated molecular weight for this EF1D protein is 35 kDa. This EF1D recombinant protein is manufactured in e.coli. The EF1D gene fragment has been modified by fusing the N-terminal 6xHis tag, providing convenience in detecting and purifying the recombinant EF1D protein during the following stages.Human elongation factor 1-delta (EEF1D) is a protein involved in protein synthesis, playing a crucial role in the elongation phase of translation. It is a subunit of the eukaryotic elongation factor 1 complex, which delivers aminoacyl-tRNA to the ribosome during mRNA translation. EEF1D specifically interacts with aminoacyl-tRNA and facilitates the accurate and efficient addition of amino acids to the growing polypeptide chain. Beyond its primary role in translation, EEF1D has been implicated in diverse cellular processes, including cytoskeletal organization, apoptosis, and regulation of gene expression. Its multifunctional nature highlights its significance in maintaining cellular homeostasis and suggests potential implications in various cellular pathways.

ACP03406

Number

Cat.No	ACP03406	Target Name	EEF1D
Form	Liquid or Lyophilized powder	Expression System	E.coli
Expression Range	2-281aa	Mol Weight	35.0kDa
Protein Length	Full Length of Mature Protein	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP03406

Target Name

EEF1D

Form

Liquid or Lyophilized powder

Expression System

E.coli

Expression Range

2-281aa

Mol Weight

35.0kDa

Protein Length

Full Length of Mature Protein

Purity

Greater than 90% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P29692

Background Information

Uniprot Id

P29692
Target Species

Human
Target Name

EEF1D
Target Full Name

Elongation factor 1-delta
Target Function

EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.; Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
Target Subcellular Location

[Isoform 2]: Nucleus.
Target Protein Families

EF-1-beta/EF-1-delta family
Target Tissue Specificity

Isoform 2 is specifically expressed in brain, cerebellum and testis.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

Antigen NY CO 4; Antigen NY-CO-4; EEF 1D; EEF1D; EF 1 delta; EF 1D; EF-1-delta; EF1D; EF1D_HUMAN; Elongation factor 1 delta; Elongation factor 1-delta; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); Eukaryotic translation elongation factor 1 delta; FP1047; Guanine nucleotide exchange protein
Target Background

This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.

Recombinant Human Elongation factor 1-delta (EEF1D)

Specifications

Immunogen Information

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