Recombinant Human EMILIN-1 (EMILIN1), Truncated

Uniprot Id

Q9Y6C2

Target Species

Human

Target Name

EMILIN1

Target Full Name

EMILIN-1

Target Function

May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.

Target Subcellular Location

Secreted, extracellular space, extracellular matrix.

Target Tissue Specificity

Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver,

Target Synonyms

Elastin microfibril interface located protein 1; Elastin microfibril interface located protein; Elastin microfibril interface-located protein 1; Elastin microfibril interfacer 1; EMIL1_HUMAN; EMILIN 1; EMILIN; EMILIN-1; Emilin1; gp115

Target Background

This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung.