Recombinant Human Endonuclease V (ENDOV)

Cat.No	ACP14874	Target Name	ENDOV
Target Synonyms	ENDOVEndonuclease V; hEndoV; EC 3.1.26.-; Inosine-specific endoribonuclease	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-282
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP14874

Target Name

ENDOV

Target Synonyms

ENDOVEndonuclease V; hEndoV; EC 3.1.26.-; Inosine-specific endoribonuclease

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-282

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q8N8Q3

Background Information

Uniprot Id

Q8N8Q3
Target Species

Human
Target Name

ENDOV
Target Full Name

Endonuclease V
Target Function

Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Active against both single-stranded and double-stranded RNAs. Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs). Cleaves mRNAs and tRNAs containing inosine. Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3'. Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing (Probable). Binds branched DNA structures.; Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Active against both single-stranded and double-stranded RNAs. Cleaves tRNAs containing inosine.; Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Active against both single-stranded and double-stranded RNAs. Cleaves tRNAs containing inosine
Target Subcellular Location

[Isoform 1]: Cytoplasm. Nucleus, nucleolus. Cytoplasm, Stress granule.; [Isoform 6]: Cytoplasm. Nucleus, nucleolus. Cytoplasm, Stress granule.; [Isoform 7]: Cytoplasm. Nucleus, nucleolus. Cytoplasm, Stress granule.
Target Protein Families

Endonuclease V family
Target Synonyms

ENDOVEndonuclease V; hEndoV; EC 3.1.26.-; Inosine-specific endoribonuclease

Recombinant Human Endonuclease V (ENDOV)

Specifications

Immunogen Information

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