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Recombinant Human Erythrocyte band 7 integral membrane protein (STOM)

ACP23717

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23717 Target NameSTOM
Target SynonymsBND7 ; EPB7 ; EPB72; Erythrocyte band 7 integral membrane protein; Erythrocyte membrane protein band 7.2 (stomatin) ; Erythrocyte surface protein band 7.2; Protein 7.2b; STOM; STOM_HUMAN; StomatinFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-288
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP27105
Background Information
  • Uniprot Id

    P27105

  • Target Species

    Human

  • Target Name

    STOM

  • Target Full Name

    Stomatin

  • Target Function

    Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.

  • Target Subcellular Location

    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle.

  • Target Protein Families

    Band 7/mec-2 family

  • Target Tissue Specificity

    Detected in erythrocytes (at protein level). Widely expressed.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    BND7 ; EPB7 ; EPB72; Erythrocyte band 7 integral membrane protein; Erythrocyte membrane protein band 7.2 (stomatin) ; Erythrocyte surface protein band 7.2; Protein 7.2b; STOM; STOM_HUMAN; Stomatin

  • Target Background

    This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants.

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