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| Cat.No | ACP05804 | Target Name | SELENOI |
|---|---|---|---|
| Target Synonyms | EPT1; EPT1_HUMAN; Ethanolaminephosphotransferase 1; hEPT1; KIAA1724; Selenoprotein I; SelI | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9C0D9 |
|---|
Uniprot Id
Q9C0D9
Target Species
Human
Target Name
SELENOI
Target Full Name
Ethanolaminephosphotransferase 1
Target Function
Ethanolaminephosphotransferase that catalyzes the transfer of phosphoethanolamine/PE from CDP-ethanolamine to lipid acceptors, the final step in the synthesis of PE via the 'Kennedy' pathway. PE is the second most abundant phospholipid of membranes in mammals and is involved in various membrane-related cellular processes. The enzyme is critical for the synthesis of several PE species and could also catalyze the synthesis of ether-linked phospholipids like plasmanyl- and plasmenyl-PE which could explain it is required for proper myelination and neurodevelopment.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
CDP-alcohol phosphatidyltransferase class-I family
Target Tissue Specificity
Widely expressed. Abundant in brain, placenta, liver and pancreas, followed by heart, skeletal muscle, lung and kidney. In brain it is strongly expressed in cerebellum, followed by the occipital pole and the frontal lobe.
Target Synonyms
EPT1; EPT1_HUMAN; Ethanolaminephosphotransferase 1; hEPT1; KIAA1724; Selenoprotein I; SelI
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