Home Products Recombinant Human Exonuclease 3′-5′ domain-containing protein 1 (EXD1)

Recombinant Human Exonuclease 3′-5′ domain-containing protein 1 (EXD1)

ACP13638

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Specifications

Cat.No	ACP13638	Target Name	EXD1
Target Synonyms	EXD1; EXDL1piRNA biogenesis protein EXD1; Exonuclease 3'-5' domain-containing protein 1; Exonuclease 3'-5' domain-like-containing protein 1; Inactive exonuclease EXD1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-514
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8NHP7

Background Information

Uniprot Id

Q8NHP7
Target Species

Human
Target Name

EXD1
Target Full Name

piRNA biogenesis protein EXD1
Target Function

RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity. The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease
Target Subcellular Location

Cytoplasm.
Target Protein Families

EXD1 family
Target Synonyms

EXD1; EXDL1piRNA biogenesis protein EXD1; Exonuclease 3'-5' domain-containing protein 1; Exonuclease 3'-5' domain-like-containing protein 1; Inactive exonuclease EXD1

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Recombinant Human Exonuclease 3′-5′ domain-containing protein 1 (EXD1)

Specifications

Immunogen Information

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