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| Cat.No | ACP13738 | Target Name | XPO6 |
|---|---|---|---|
| Target Synonyms | Exp6; Exportin 6; Exportin-6; RAN binding protein 20; Ran-binding protein 20; RANBP20; xpo6; XPO6_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96QU8 |
|---|
Uniprot Id
Q96QU8
Target Species
Human
Target Name
XPO6
Target Full Name
Exportin-6
Target Function
Mediates the nuclear export of actin and profilin-actin complexes in somatic cells.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
Exportin family
Target Synonyms
Exp6; Exportin 6; Exportin-6; RAN binding protein 20; Ran-binding protein 20; RANBP20; xpo6; XPO6_HUMAN
Target Background
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
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